by G. Derek Weiss, MD, FACS, FASMBS
Introduction
Weight regain years after successful gastric bypass surgery is a fairly common therapeutic challenge facing today’s practicing bariatric surgeon. The majority of weight loss after Roux-en-Y gastric bypass (RYGB) tends to occur during the first 1 to 2 years postoperatively and averages 65 to 80 percent of excess body weight loss (EBWL).1-3 Magro et al recently showed that at two years, as many as 50 percent of RYGB patients had gained at least some weight from their nadir weight, with an average weight regain of some 8.8kg in that particular subset at five years.3 Other prospective studies have shown a weight regain of 20 percent of patients at 10 years.4 Well understood now in the medical community is the negative impact that this excess weight has on the incidence of cardiovascular, metabolic, orthopedic, and pulmonary disease.

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